Pathology of the Upper GI Tract

Recall the common infectious and inflammatory conditions encountered in the upper GI tract.
Describe the histological and endoscopic changes in Barrett’s oesophagus and understand its aetiology, pathogenesis and complications, including oesophageal cancer…
Discuss the causes and complications of peptic ulceration and Helicobacter pylori infection
Describe the classification of gastritis (acute vs. chronic, autoimmune, bacterial and chemical)

Let’s remind ourselves of the normal GI wall structure…
Look at the histology of the normal oesophageal mucosa…
Explain what squamous dysplasia is, and how it looks!
Now, look at an invasive squamous carcinoma in the tongue…
Explain the pathology of reflux oesophagitis…
What other pathologies can affect the oesophagus?
Look at candida oesophagitis…
Here’s a pathology sample that presented from a 62 year old female with oesophageal erosion…
What are the symptoms of eosinophilic oesophagitis, and how is it characterised?
Explain what Barrett’s oesophagus is…
Here’s examples of dyplastic changes in Barrett’s oesophagus…
What are the risks with Barrett’s Oesophagus?
What are the associations with different types of oesophageal cancer?
Outline the different pathologies we can get in the stomach…