ILOs

• Understand difference between chronic & acute leukaemia
• Identify them as a ‘bone marrow cancer’ due to acquired genetic abnormalities
• Have a basic understanding of classification
• Have a basic understanding of management
• Understand the basic definitions of the terms myelodysplasia (MDS) and myeloproliferative disorders (MPD)
  • Understand that these are not ‘leukaemias’ as such
  • Understand that they have a variable clinical outcome (from very good to very poor) and only a minority transform (to AML)

• What is leukaemia?
• Outline the different classifications of leukaemia…
• How does leukaemia occur?
• What are the symptoms caused by in different types of leukaemia?
• Explain the pre leukaemic conditions that we’re expected to know about

Acute Leukaemia

• What is acute leukaemia?
• A simple diagram of haemopoiesis showing how the acute leukaemias develop
• How does the incidence of AML change with age?
• Outline the aetiology of acute leukaemia
• What sort of findings do we find on history and examination with acute leukaemia?
• What would you see in peripheral blood?
• How do we actually diagnose acute leukaemia?