ILOs

• Understanding of
  • Thyroid hormone synthesis
  • Thyroid hormone regulation
  • Thyroid hormone action
  • Thyroid disorders
    • Hyperthyroid
    • Hypothyroid

• What are Thyroid disorders?
• What is the Thyroid gland made of?
• What are Follicular cells?
• Why is Iodine important in the Thyroid?
• What is thyroglobulin made of and what is it used for?
• How is the Thyroid Hormone biosynthesised (Iodine chemical gradient)?
• How is the Thyroid Hormone biosynthesised (Oxidation & Organification)?
• How is the Thyroid Hormone biosynthesised (forming DIT/MIT)?
• Summarise the above 3 toggles
• How is thyroid hormone synthesised?
• Describe the process of Thyroid hormone deiodination
• What is the chemical structure of Circulating thyroid hormones and what is it used for?
• Describe Thyroid hormone action
• Which systems do Thyroid hormones affect?

Thyroid Disease

• How is TSH regulted?
• What happens to this during primary/secondary hyperthyroidism?