ILOs:

• Define the cell cycle, describe its various stages and outline how it is normally regulated
• Explain what happens during each phase
• Explain what a checkpoint is
• Describe how major checkpoints work
• Describe the function & regulation of cyclin-dependent kinases (CDKs)
• Explain how p53 and RB function as tumour suppressors

• Definition
• Do all cells cycle?
• Phases of the cell cycle
• G0
• The length of the cycle
• Regulation of the cell cycle
• Why do we need to understand the cell cycle?