ILOs:

• List the normal functions of the liver
• Describe the structure of the liver in terms of its broad anatomy and histology
• Describe the liver’s vasculature, parenchyma and biliary system and its normal connective tissue
• Briefly describe the contents of bile and how it is produced and secreted. Describe how jaundice may arise
• List the so-called “liver function tests” (LFTs)
• Briefly describe what abnormality of any one LFT may mean and outline the pattern of abnormal LFTs in jaundice of different causes
• Define cirrhosis and describe its pathogenesis, causes and possible complications
• Describe the effects of liver failure

Part 1: Normal Structure and Function

• Diagram showing where the liver is situated in the body
• Outline some functions of the liver
• What structures are situated around the liver?
• What are the different types of tissues found in the liver?
• Outline key structures in the liver vasculature
• Describe the structures in the portal triad
• Outline the structure and function of hepatocytes
• What adaptations allow the sinusoidal surface to carry out their function?
• Name some of the most common parenchymal liver cells