ILOs:

• Explain the terms genome, transcriptome and proteome
• Explain how the genetic code gives rise to different amino acids and polypeptides
• Describe how the properties of an amino acid (and the resulting polypeptide) are determined by the R group
• Use examples to describe how post-translational modifications can alter protein function
• Briefly describe how proteins are produced from RNA
• Describe in general terms how proteins are localised to different parts of the cell
• Explain what is meant by primary, secondary, tertiary and quaternary protein structure
• Use examples to explain how mutations alter protein function and result in disease

• The three levels of information
• Bioinformatics
• The genetic code
• mRNA
• Amino acids
• Proteins