ILOs:

• Describe ionic distribution across cell membranes
• Explain its maintenance using metabolic energy
• Describe its electrical consequences (a) in resting cells (b) in electrically active nerve or muscle
• Contrast transmission of a signal from nerve to skeletal muscle with propagation along the length of either individual cell
• Describe the microscopic structure of skeletal muscle fibre.
• Describe the organisation of contractile proteins, and (a) their participation in muscle length change (b) how they make muscle contract
• Explain how electrical excitation leads to contraction

• Types of muscle
• Resting membrane potential
• Muscle excitation
• Microanatomy of skeletal muscle
• Muscle contraction
• Energy storage and delivery
• The nature of muscle contraction
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