Lecture: Measuring Kidney Function

Understand how substances such as creatinine are “cleared “by the kidneys
Understand how kidney function can be assessed by measurement of glomerular filtration rate
Explain how estimated GFR measurements are made, and the limitations of this measurement
List typical values for renal blood flow, glomerular filtration rate and urine production

Recap: what are the functions of the kidenys and what are they all dependent upon?
What does GFR measure?
What is clearance and how is it measured?
How do you Measure GFR and what is its calculation?
Which exogenous substance is infused when measuring kidney function?
Which exogenous substance is used when measuring kidney function in hospitals?
What else may be used instead of exogenous compunds, to measure GFR?
How is creatinine made by the body?
What is the calculation for Creatinine clearance? (similar to before)
Since even measuring creatinine isn't ideal, what is the alternative?
Tanks demonstrating physiology
What happens to GFR as serum creatinine increases?
Disadvantages of using serum creatinine for estimating GFR?
Cockcroft and Gault formula for estimating creatinine clearance - Dont need to learn these formulae