ILOs:
- Revise the anatomy of the liver
- Describe the normal functions of the liver
- Discuss about liver marker in health and pathological situation
- Interpret liver function markers to confirm liver disease
- Discuss use of liver function tests in clinical contexts – case review
Theory
- What are liver function tests?
- What does a conventional LFT profile include?
- Why might we request a LFT?
- What is bilirubin?
- Outline the different types of hyperbilirubinaemia
- What are the aminotransferases, and what do they mark?
- What is y-Glutamyl transferase (GGT)?
- What's the link between GGT and excess alcohol consumption?
- What's alkaline phosphatase?
- Which plasma proteins get synthesised in the liver?
- Important principles to remember
- What are reference intervals for LFTs defined for?