ILOs
- Understand the distinct roles of the blood coagulation cascade and of blood platelets in haemostasis following haemorrhage
- Explain the endogenous mechanisms that normally suppress blood coagulation and platelet activation
- Understand the mechanisms by which inappropriate intravascular activation of the coagulation cascade and of blood platelets occurs in venous and arterial thrombosis, respectively
- Explain the origins of clotting disorders (haemophilias) arising from deficiencies in blood coagulation factors
- What is haemostasis?
- What is thrombosis?
- What are platelets/thrombocytes?
- How many platelets are there per microlitre of blood?
- What is clinical cutoff for platelet deficiency?
- How is intravascular blood coagulation and platelet activation suppressed naturally?
- How are platelets activated following vascular damage?
- What is the coagulation cascade and what does it result in?
- Outline the coagulation cascade factors and all the factors involved
- Diagrammatic representation of the accelerant nature of the coagulation cascade
- Outline some common blood clotting disorders and the result of them?
- Outline the fibrinolytic system and its outcome
- What are the differences between venous and arterial thromboses and therapy?