ILOs:

• Define terms including proto-oncogene, oncogene, tumour suppressor gene (tsg), neoplasm and cancer
• Describe the functions of proto-oncogenes and tsgs in normal cells, giving examples
• Explain how mutation can lead to activation of proto-oncogenes
• Explain how (proto-)oncogene activation and loss of tsgs can lead to cancer
• Describe briefly the molecular changes that allow a tumour cell to metastasise (spread).

• Terminology
• Cancer cell morphology
• What happens to a normal cell to become cancerous?
• Characteristics of cancer
• How this knowledge allows us to treat cancer