ILOs

• Describe the concepts of acid – base physiology.
• Describe clinical syndromes of disordered acid – base balance.
• Describe the concept of renal compensatory function in relation to respiratory acidosis.

Part 1 - Basic Concepts

• What is an acid? What is a base?
• How is H+ found and measured in solution?
• How does H+ and pH relate?
• Why does regulation of [H+] matter?
• Outline the effects of acid-base disorders
• What threats does the body face to acid-base homeostasis?
• What mechanisms does the body have to maintain acid-base homeostasis?
• What is the fundamental concept we need to remember in acid-base homeostasis?
• A patient case...
• What is a buffer?
• Outline the Henderson-Hasselbach Equation
• How does physiological buffering occur?
• Cartoon explaining buffering!
• Which other buffering systems do we have?