ILOs:

• Explain the 'health and safety' precautions associated with taking and handling blood.
• Measure blood glucose using an electronic device designed for home use.
• Describe the method employed in the electronic assay for glucose.
• Measure urinary metabolites using Clinistiks and explain the basis of the method.
• Construct a graphical representation of your Glucose Tolerance Test and explain its main features.
• Describe how the Glucose Tolerance Test of a person with diabetes would differ from that of a healthy individual.
• Describe the fate of glucose ingested in the test dose for the Glucose Tolerance Test in both individuals with and without diabetes.
• Describe metabolic and hormonal changes occurring in the body during the period of the test.

Introductory Video

• What enzyme does our blood glucose sensor use?
• So how does the blood glucose sensor work?
• How does the urine glucose strip work?
• What happens in the oral glucose tolerance test?

n.b. watch video in the lab to watch the test being carried out

• A table explaining what oral glucose tolerance test results mean

Worksheet Questions

• I consumed a known amount of glucose which has a molecular weight of 180g/mole. Calculate how many moles of glucose were consumed (Lucozade = 32.5g glucose, Mars bar = 35g glucose)
• If all of the glucose I consumed remained in the bloodstream, what would its concentration be? (you will need to estimate a value concerning my physiology)