ILOsgreen, blue, yellow, pink, purple, ilo 6 missing, red:

• Discuss protection of the gastric mucosa against effects of excess gastric secretions
• Describe the physiological regulation of gastric acid secretion
• Describe the 24 hour intragastric pH profile and the factors which affect it
• Discuss the various methods available to diagnose Helicobacter pylori infection
• Describe the mechanisms by which Helicobacter pylori infection predisposes to duodenal ulcer disease
• List the different types of drug treatment which might be effective against peptic ulcers, and discuss their mechanism of action

Part 1: Physiology of Acid Secretion

• What is peptic ulcer disease largely due to?
• Diagram showing gross anatomy of the stomach
• Which type of glands mainly line the gastric body?
• What is the stimulus for acid secretion?
• Which factors control gastric secretion?
• Which chemicals make up gastric juice?
• A diagram outlining the processes that underpin gastric secretion
• Diagram of the wall of the parietal cell
• What are the components of gastric acid, and why is it important?

Part 2: Pathophysiology of Acid Related Diseases

• How does the type of epithelium vary in the upper gastrointestinal tract?