ILOs:

• The role of the pancreas in the digestion of food in the human gut.
• The products of digestion and where they are released for absorption.
• Different specificities of the pancreatic endopeptidases trypsin and chymotrypsin and the structural basis for these specificities.
• The actions of amylase on different dietary carbohydrates and the products released.
• Clinical tests available for pancreatic function and interpretation of the results.

Pancreatic secretions

• What roles does the pancreas play?
• Diagram giving an overview of pancreatic secretions
• Examples of different pancreatic enzymes and their roles
• Diagram showing bicarbonate secretion
• Diagram showing activation of proteolytic enzymes
• Sequence of protein digestion

Investigating specificity of enzymes

• What are the products of amylase digestion?
• What are non-digestible carbohydrates?
• What are reducing sugars?
• What's the difference between salivary and pancreatic amylase?

Experiment 1: Action of amylase