ILOs:
- Describe the histology of the pancreas - recognise and distinguish different cell types
- Explain the basis of immunocytochemical techniques and how they can be used to identify molecular functions of cells
- Distinguish, using immunocytochemical observations, between normal and failing function of specific cell types
- Describe the histological structure and physiological function of the adrenal cortex
- Describe the structure and function of the adrenal medulla
Part 1: Histology of the pancreas
- Some useful definitions
- When we think of endocrine organs we can think of cells as being in 1 of 3 distinct arrangements:
- Which 2 buds does the pancreas develop from in the embryo?
- What do these ducts go on to form?
- Where are the islets most numerous?
- What is the size of each islet?
- What features help you identify the islet in the following slide?
- What if we use this same section and zoomed in?
- What are the 2 types of cells in the pancreas?
- What stain can we use to differentiate between those 2 types?
- What would we see if we zoomed in?
- Even further...