ILOs

• understand how and approximately when HIV arose in the human population understand HIV epidemiology both worldwide and in the UK
• understand the routes of transmission of HIV
• understand the virus genome structure and its method of replication both within a cell and an individual
• understand the importance of latency in HIV infection
• describe the viral targets for an antiviral approach describe the importance of monitoring antiviral resistance
• briefly describe current attempts to develop a vaccine against HIV
• provide an overview of the clinical manifestations of HIV/AIDS
• describe the natural history of HIV infections explain clinical monitoring of HIV
• consider the impact of HIV therapy
• describe the relationship between HIV and sexual health
• review the wider politics and social dimensions of HIV/AIDS

Clinical

• The main message to take away from this lecture…
• Outline the current situation with HIV testing in the UK…
• Which populations are at highest risk of HIV?
• What test do we use right now for HIV, what antigen is it looking for and what is the window period?
• What is seroconversion?
• What are the differentials to bear in mind with a rash that looks like it could be primary HIV infection?