Glomerulonephritis (GN)

Describe the aetiology of acute and chronic glomerulonephritis
Correlate the clinical and pathological features of differing types of glomerulonephritis
Discuss the diagnosis of glomerulonephritis
Outline the treatment and prognosis of acute and chronic glomerulonephritis diseases affecting the urinary tract

So, what is glomerulonephritis?
Here’s a slide from the Scottish Renal Registry which outlines the spread of kidney disease…
Outline the approach to glomerulonephritis…
What are the targets of the glomerulus that can be damaged in glomerulonephritis?
List the pathophysiological mechanisms behind glomerulonephritis…
What is the only way we can know exactly what’s going on in glomerulonephritis?
Look at two 1cm pieces of kidney cortex…
Now, time for a H&E stain of the kidney…
So, explain what a kidney biopsy shows to a pathologist?
Look at the main patterns of glomerulonephritis…
So, how do we reach our diagnosis?
What is the primary abnormality in glomerulonephritis?
Outline the clinical spectrum of glomerulonephritis…
Describe the triad of nephrotic syndrome to us, and what it increases your risk of…