ILOs

Understand the pathophysiology, investigations and treatment of…

• Cushing’s Syndrome and Disease
• Hypoadrenalism
• Congenital Adrenal Hyperplasia
• Pheaochromocytoma
• Primary Hyperaldosteronism
• The Adrenal Incidentaloma

Revision

• Let’s remind ourselves of the anatomy of the adrenal gland…
• Let’s also remember the renin-angiotensin-aldosterone system…
• Remember the action of aldosterone…
• And, here’s the hypothalmic-pituitary-adrenal axis…
• Which factor controls the production of adrenal androgens?

Cushing’s Syndrome and Disease

• Here’s our patient case 1…
• Look at the clinical features of Cushing’s Syndrome…
• When someone has features of Cushing’s, what’s the first question we ask and investigate?
• Outline the causes of Cushing’s Syndrome…